It is important to follow these instructions religiously. JC. document.getElementById( "ak_js_1" ).setAttribute( "value", ( new Date() ).getTime() ); This website is a resource which lists doctors and clinics who may offer phentermine or appetite suppressants for patients they deem qualified. Another important fact to consider before taking Phentermine is that it should never be used by women who are pregnant or who are currently breastfeeding. Phentermine is a Schedule 4 drug. Phentermine is a popular prescription drug that is often used to treat obesity. In some cases, the side effects were life-threatening and led to the death of a patient. Children 15 years of age and youngerUse is not recommended. Phentermine is related chemically and pharmacologically to amphetamine (d- and dll-amphetamine) and other related stimulant drugs have been extensively abused. Review/update the If you miss a dose of this medicine, take it as soon as possible. The weight loss experts who OSMA has consulted with have indicated that misuse of phentermine is unlikely. Today, Phentermine can still be obtained through the doctors prescription in the majority of countries around the world. In most cases, the drug is prescribed to users in periods of 12 weeks. It should melt quickly. Phentermine was later provided to patients in combination with dexfenfluramine and fenfluramine as a more powerful appetite suppressant that could also act as a fat burner. Concomitant use of alcohol with phentermine may result in an adverse drug reaction. 4 The Formulary can be accessed on the Board of Nursing website: www.nursing. It is obvious that these symptoms can make the entire program useless. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. "@Hw4`tqCA\+ q [AF]` b L ! Phentermine hydrochloride/topiramate. However, it caused a chronic condition known as pulmonary hypertension, which led to the death of many patients. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. (1/19/2016) Ohio Strenthens Opioid Prescribing Guidlines to Further Prevent Prescription Drug Abuse and Save . hb```e````a`d`@ f(fcfILLvL~. The strength and dosage of Phentermine depend on the brand that is prescribed and the patients specific condition. Other initial symptoms may include angina pectoris, syncope or lower extremity edema. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education. Due to its status as a controlled substance, the sale, distribution, and possession of this drug is tightly regulated by the DEA and international regulatory authorities ( Phentermine hydrochloride (phentermine HCL) is the active ingredient in phentermine weight loss pills. In relatively short-term clinical trials, adult obese subjects instructed in dietary management and treated with anorectic drugs lost more weight on the average than those treated with placebo and diet. Store at 20 to 25C (68 to 77F) [See USP Controlled Room Temperature]. HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use . Phentermine may decrease the hypotensive effect of adrenergic neuron blocking drugs. Want to get more tips, information, and motivation? This medication has been linked to physical dependence, which means a patient may become addicted to it. This search engine indexes the Drug Enforcement Administration Diversion Control Program Web Site (www.deadiversion.usdoj.gov) only. Carefully follow the dosing instructions for the form you are using. A physician is the only person who can prescribe phentermine. The structural formula is as follows: Phentermine hydrochloride is a white, odorless, hygroscopic, crystalline powder which is soluble in water and lower alcohols, slightly soluble in chloroform and insoluble in ether. The drug is usually prescribed at the lowest possible dose to new users, which is 15mg per day. It's designed to help prevent opioid dependence for Ohio's injured workers through its three primary goals. Abuse of amphetamines and related drugs may be associated with intense psychological dependence and severe social dysfunction. 138 0 obj <>stream Phentermine has not been studied in patients with eGFR less than 15 mL/min/1.73m2, including end-stage renal disease requiring dialysis; avoid use in these populations. The possibility of an association between valvular heart disease and the use of Phentermine alone cannot be ruled out; there have been rare cases of valvular heart disease in patients who reportedly have taken Phentermine alone. Phentermine is approved for use for up to 12 . , ADIPEX-P (phentermine hydrochloride) tablets, for oral use CIV ADIPEX-P (phentermine hydrochloride) capsules, for oral use CIV Initial U.S. Approval: 1959 While discussing the use of Phentermine with the doctor, a patient is provided a list of lifestyle changes to implement while using this product. It is vital to talk with the doctor before using Phentermine with other products. It has the chemical name of ,,-Dimethylphenethylamine hydrochloride. It is both dangerous and potentially illegal to use an online phentermine doctor. hbbd``b` @IHpA\> . information submitted for this request. Apart from these brand names, other brands that contain the drug as part of their multi-ingredient formula also exist and the most popular one is Qsymia. The following information includes only the average doses of this medicine. Some patients need to take the drug an hour before they eat breakfast, while others are advised to take it approximately one to two hours after breakfast. Our mission is to Empower, Unite, and Advance every nurse, student, and educator. Do not crush, break, or chew it. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Phentermine HCl Tablets, USP 37.5 mg Learn about phentermine and succeed in your weight loss journey. The combined drug is approved for long-term use. Phentermine is not to be used while pregnant or breastfeeding under any circumstances. The first use of Phentermine as a drug to help treat obesity dates back to 1938. If you are a Mayo Clinic patient, this could %PDF-1.3 While this drug may sound like a wonder pill, patients should ensure they know are familiar with the precautions, interactions, side effects and other important details before they start taking it. A doctor is the only person who can determine if phentermine is right for you. Even patients who are overweight and pregnant at the same time are not allowed to use this product. Rule 4731-11-04 | Controlled substances: Utilization of short term anorexiants for weight reduction. Special Populations Geriatric Patients Select dosage with caution, starting at lower end of dosage range. These are two schedule- IV medications, phentermine/topiramate (Qsymia), and locaserin (Belviq), as well as non-controlled naltrexone hydrochloride/ buproprion hydrochloride (Contrave). Phentermine is a sympathomimetic amine with pharmacologic activity similar to the prototype drugs of this class used in obesity, amphetamine (d- and dll-amphetamine). Long-term efficacy and safety of anti-obesity treatment: Where do we stand? More specifically, this medication is an option for people with a body mass index (BMI): Weight-related conditions that may qualify a lower-BMI patient for phentermine include: type 2 diabetes, high cholesterol (hyperlipidemia), and controlled high blood pressure (hypertension) ( Although phentermine is the agent-of-choice among physicians specializing in obesity treatment, the use of this drug for obesity treatment by other physicians has long been curtailed because misapprehensions regarding phentermine safety. Your doctor may prescribe both of these drugs separately, or choose to prescribe Qsymia, which is another medication that combines Phentermine and Topamax. CIV This was often referred to as Rainbow Pills as all four drugs were often provided to a patient at the same time. (phentermine hydrochloride) orally disintegrating tablet C IV . Below is a chart of body mass index (BMI) based on various heights and weights. A link to Chapter 4731-11, OAC, is also provided on page 15 of the Formulary.The nursing law and rules are available for review on the Boards website www.nursing.ohio.gov under the Law and Rules link.The website for State Medical Board of Ohio is: www.med.ohio.gov. Drug classes: Anorexiants, CNS stimulants. In order to determine the effectiveness of certain pharmaceuticals, supplements and other substances, clinical trials and scientific research are often conducted among a group of volunteers. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. They help the body produce a larger amount of energy from fat cells, which further reduces body fat percentage. Adults and children 17 years of age and older. Precaution should be taken if a patient has any existing health concerns as the drug may cause further harm to their body. Your email address will not be published. In fact, one study conducted at the Duke University School of Medicine found that apart from the Phentermines ability to effectively reduce body weight, it can also help improve a patients health-related quality of life. Based on the reported excretion of Phentermine in urine, exposure increases can be expected in patients with renal impairment [see ClinicalPharmacology (12.3)]. The overdose symptoms include: The side effects of Phentermine can lead to several symptoms that may impair certain functions in the patients body. See DrugAbuse and Dependence (9.3). The patient could have had the prescription for the month of October filled at another pharmacy. Studies have not been performed with Phentermine to determine the potential for carcinogenesis, mutagenesis or impairment of fertility. LiverTox National Institutes of Health. More specifically, this medication is an option for people with a body mass index (BMI): Greater than 30 kg/m2 Greater than 27 kg/m2 + one or more weight-related condition Phentermine may impair the ability of the patient to engage in potentially hazardous activities such as operating machinery or driving a motor vehicle; the patient should therefore be cautioned accordingly. The safety and efficacy of combination therapy with Phentermine and any other drug products for weight loss including prescribed drugs, over-the-counter preparations, and herbal products, or serotonergic agents such as selective serotonin reuptake inhibitors (e.g., fluoxetine, sertraline, fluvoxamine, paroxetine), have not been established. A reduction in insulin or oral hypoglycemic medications in patients with diabetes mellitus may be required. Le81g Of Rdb-YR!bLEbfYo9(e Phentermine is a popular prescription drug that is often used to treat obesity. Phentermine Hydrochloride Tablets are indicated only as short-term (a few weeks) monotherapy for the management of exogenous obesity. Some weight loss clinics also insist that patients take additional supplements, such as vitamin B12 shots and 5-HTP, to boost phentermine despite the supplements unproven effectiveness. Phentermine. The dosage may be adjusted to the patients need. %%EOF Medically reviewed by Drugs.com. This is a label given to drugs that can be misused. Phentermine hydrochloride: Usual dosage is 8 mg 3 times daily (given 30 minutes before meals) or 15-37.5 mg once daily (in the morning). He or she may prescribe the medication him/herself if you are an appropriate candidate, or he/she may choose to refer you to a specialist for further evaluation and follow-up. Tablets containing 37.5 mg Phentermine hydrochloride (equivalent to 30 mg Phentermine base). Dosage should be individualized to obtain an adequate response with the lowest effective dose. The drug is also available in regular capsules that are taken orally with a glass of water. Primary Pulmonary Hypertension (PPH) a rare, frequently fatal disease of the lungs has been reported to occur in patients receiving a combination of Phentermine with fenfluramine or dexfenfluramine. It also isn't for people who are pregnant, may become pregnant or are breastfeeding. To avoid trouble with sleeping, take the last dose of the day about 4 to 6 hours before bedtime, unless your doctor tells you otherwise. The use of Topamax and Phentermine is actually an FDA-approved combination. The possibility of abuse of Phentermine should be kept in mind when evaluating the desirability of including a drug as part of a weight reduction program. Safety and effectiveness in pediatric patients have not been established. Especially considering Ohios ability to track the prescribing and dispensing of the drug in Ohios drug database, OARRS. Typical actions of amphetamines include central nervous system stimulation and elevation of blood pressure. It helps patients lose weight by suppressing their appetite and boosting their energy levels, thus leading to a more active lifestyle and greater calorie burn. The drug is always accompanied by increased physical activity and a diet that includes a lower amount of calories. Sign-up for our weekly newsletter! Animal reproduction studies have not been conducted with Phentermine. Phentermine is intended to help overweight and obese patients who have already tried losing weight with diet and exercise. History of cardiovascular disease (e.g., coronary artery disease, stroke, arrhythmias, congestive heart failure, uncontrolled hypertension), During or within 14 days following the administration of monoamine oxidase inhibitors, Known hypersensitivity, or idiosyncrasy to the sympathomimetic amines, Effect on the ability to engage in potentially hazardous tasks [see, Withdrawal effects following prolonged high dosage administration [see, Development of primary pulmonary hypertension [see, Development of serious valvular heart disease [see, Effects on the ability to engage in potentially hazardous tasks [see, The risk of an increase in blood pressure [see, the potential for developing tolerance and actions if they suspect development of tolerance [see, the risk of dependence and the potential consequences of abuse [see. While the drug is considered to be relatively safe for individuals who are older than 16, the recommended age is 18. The most common side effects that patients experience include tremors, headaches, dizziness, dry mouth, diarrhea, constipation, upset stomach, feeling restless and being hyperactive. Before writing a phentermine prescription, he or she will evaluate your: While any doctor can prescribe phentermine, not all doctors feel comfortable doing so. Obesity has been linked to many different diseases, including type 2 diabetes and cardiovascular disease. 1591 0 obj <>stream Rule 4731-11-03 | Utilization of anabolic steroids, schedule II controlled substance cocaine hydrochloride, and schedule II controlled substance stimulants. Manifestations of acute overdosage include restlessness, tremor, hyperreflexia, rapid respiration, confusion, assaultiveness, hallucinations, and panic states. When breastfeeding, the drug may enter the breast milk and travel into the nursing babys body, which may cause harm to them. Dosage form: tablet endstream endobj 1531 0 obj <>/Metadata 26 0 R/Pages 1528 0 R/StructTreeRoot 41 0 R/Type/Catalog>> endobj 1532 0 obj <>/Font<>/ProcSet[/PDF/Text]>>/Rotate 0/StructParents 0/Tabs/S/TrimBox[0.0 0.0 630.0 702.0]/Type/Page>> endobj 1533 0 obj <>stream Our members represent more than 60 professional nursing specialties. 2 Thus, in order to make the most of this drug, patients need make some effort too. Cumulative urinary excretion of Phentermine under uncontrolled urinary pH conditions was 62% to 85%. Please consult with your physician before you make any decisions regarding your health. Succeed on your weight loss journey with our curated resources! Dr. Lazarus, we will discuss combination phentermine therapy later in this roundtable discussion. If your dose is different, do not change it unless your doctor tells you to do so. The magnitude of increased weight loss of drug-treated patients over placebo-treated patients is only a fraction of a pound a week. Click here for an email preview. Do not crush, break, or chew it. %PDF-1.6 % N;d0)zQ|,]8EtXy(En"GX omjU3Y3>kfkYHYi]-zhm{= o`i$G1BK%?9Z+(dm`mKt,?;6K@Q 7}}*Tw>7BkKsJ;E|Viexb T-3j%5QB%wI5'$5oB :h*C"Q7yjTzLO%6QS/u>HX 4DGz*A!1*p"7$-joX2YF8ht@\l[&LS$FU=udM&y.l_ ). (1981, February 4). What could be the cause? Lomaira: One tablet three times a day, taken 30 minutes before meals. The Topamax is added to Phentermine in order to intensify its effects and to help patients lose weight faster. allnurses is a Nursing Career & Support site for Nurses and Students. CTP holders continue to be prohibited from prescribing all other anorexiants including, but not limited to phentermine (Adipex). She is passionate about promoting health at any size. other information we have about you. It isnt prescribed on request, but rather when a healthcare provider notices it may be beneficial for a specific patient to lose weight in order to improve their overall health or to decrease the risk of certain health concerns. Phentermine is intended to help overweight and obese patients who have already tried losing weight with diet and exercise. Last updated on Mar 22, 2022. Some people also receive a phentermine prescription from their gynecologist (OB-GYN).